Keck Medicine of USC is set to open a new, four-story, 100,000-square-foot medical office building at 590 S. Fair Oaks Ave. in Pasadena by Fall 2025.
By News Desk
The new facility will significantly expand clinical care for residents in Pasadena and the surrounding San Gabriel Valley.
This location will become Keck Medicine’s largest and most advanced outpatient center, offering a comprehensive range of services to meet the evolving health needs of the local community. It will bring cutting-edge, research-based clinical care to an area where many of the health system’s patients already live and work.
Rod Hanners, CEO of Keck Medicine, expressed his enthusiasm for the new facility:
This new location will bring even more of our research-based clinical care to the Pasadena area, where many of our patients live and work. The new location offers state-of-the-art technology and access to acclaimed specialists who translate medical discoveries into groundbreaking treatments and cures.”
A Wide Range of Specialized Services
The new office building will offer various medical services, including care for autoimmune diseases, rheumatology, allergy/immunology, cardiovascular care, comprehensive oncology, infusion therapy, orthopedics and spine care, outpatient imaging, outpatient surgery, pain management, and physical therapy.
A standout feature of the facility is that patients will have access to the same expert physicians who treat patients at Keck Medical Center of USC. This includes specialists from USC Norris Comprehensive Cancer Center—one of the nation’s top cancer centers—the USC Cardiac and Vascular Institute, and the USC Orthopaedic Surgery team, who also provide medical services to USC Athletics and the LA Kings.
A Healing, Nature-Filled Environment
The building will feature an airy, light-filled environment with floor-to-ceiling windows offering breathtaking views of the San Gabriel Mountains. The top floor will include a fully landscaped terrace that opens onto a healing garden, providing a calming and restorative space for both patients and visitors.
Breakthrough Cancer Treatment
Keck Medicine will be the first and only university-based academic health system in Southern California to offer biology-guided radiation therapy. This innovative technology delivers real-time signals about the location of cancer cells, enabling radiation oncologists to precisely target and treat cancer cells while minimizing damage to surrounding healthy tissue. Recently granted breakthrough device designation by the U.S. Food and Drug Administration, this therapy is approved for certain patients with lung and bone tumors.
Smitha Ravipudi, MPH, CEO of USC Care Medical Group and CEO of Keck Medicine’s ambulatory care services, emphasized the significance of the new facility:
The new Pasadena medical office building doubles down on our commitment to the health of our community, allowing patients to visit one location for a variety of health care needs while providing access to the high-quality care only an academic health system can offer.”
Expansion and Continuation of Care
In addition to the new location, Keck Medicine will continue to serve patients at its existing Keck Medicine of USC – Pasadena building at 625 S. Fair Oaks Ave., Suite 400. This existing facility will expand its range of primary care services, focusing on digestive and metabolic health, brain health and aging, and advanced ear, nose, and throat care, as well as ophthalmology services.
Keck Medicine of USC, part of one of only two university-based health systems in the Los Angeles area, ranks among the top 50 hospitals in the nation in eight specialties and is consistently recognized as one of the top hospitals in metro Los Angeles and California.










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